Experience with Bretylium Tosylate By a Hospital Cardiac Arrest Team DOUGLAS
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چکیده
8. Greenblatt DJ, Duhme DW, Koch-Weser J, Smith TW: Intravenous digoxin on a bioavailability standard: Slow infusion and rapid injection. Clin Pharmacol Ther 15: 510, 1974 9. Preibisz JJ, Butler VP Jr, Lindenbaum J: Digoxin tablet bioavailability: Single-dose and steady-state assessment. Ann Intern Med 81: 469, 1974 10. Huffman DH, Manion CV, Azarnoff DL: Absorption of digoxin from different oral preparations in normal subjects during steady state. Clin Pharmacol Ther 16: 310, 1974
منابع مشابه
Experience with bretylium tosylate by a hospital cardiac arrest team.
The effect of bretylium tosylate (BT) was determined in 27 consecutive cases of resistant ventricular fibrillation (VF) encountered by a hospital cardiac arrest team. The VF was sustained and completely resistant to multiple injections of lidocaine, sequential DC shocks at 400 watt-sec and one or a combination of intravenous propranolol, diphenylhydantoin or procainamide. Following 30 min of su...
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The prophylactic value of parenterally administered bretylium tosylate against the onset of dysrhythmias after acute myocardial infarction has been assessed by a controlled trial in 101 male patients. Bretylium significantly reduced the incidence of supraventricular dysrhythmias but was without significant effect on the incidence of ventricular dysrhythmias. The only serious side-effect of the ...
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In IO patients with severe myocardial infarction and left ventricular failure, bretylium tosylate was used in the treatment of ventricular arrhythmias which had proved refractory to lignocaine and procainamide; 6 cases had also failed to respond to phenytoin. In 7 patients stable sinus rhythm was achieved and 5 of these survived to leave hospital. For the period during which bretylium was used,...
متن کاملEffectiveness of bretylium tosylate against refractory ventricular arrhythmias.
Thirty patients with ventricular tachyarrhythmias, which had not responded to intensive therapy with up to five antiarrhythmic drugs, were treated with bretylium tosylate. All patients had recurrenit ventricular tachycardia, and 12 had repeated episodes of ventricular fibrillation. In 17 patients the arrhythmias followed acute myocardial infarction. Bretylium was administered intramuscularly or...
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Cardiac arrhythmias following acute myocardial infarction are often fatal. Although commonly used antiarrhythmics are usually effective, some patients develop dysrhythmias that are refractory to these medications. This article discusses the use and contraindications of bretylium tosylate, a relatively new antiarrhythmic drug that has been shown to be effective in reversing dysrhythmias that wer...
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